`Dhol - Kiska Bajega` revolves around the lives of four friends - Sam (Tusshar Kapoor), Pakkya (Sharman Joshi), Maru (Rajpal Yadav) and Goti (Kunal Khemu). The guys are good for nothing with no motivation. But they`re bound together by their child-like notoriety and aimlessness. They all want to make it big in life with the least efforts possible. The four wish to live life on their own terms, leading everyone to nowhere. As a result, each one tries their hand at finding a short cut to success but ends up being in even deeper trouble instead. Things get worse as the four decide to take some desperate measures to end their misery once and for all.
According to them, the only way to get rich without working hard is to get married to a rich girl. Surprisingly, to unlock their fates, arrives the rich girl Kanchan (Tanushree Dutta) in their neighborhood. All four set out with their individual plans to marry Kanchan but end up discovering a spine-chilling truth.
This leads to much confusion, creating hilarious twists and turns, along with an element of thrill, crime, murder and suspense.