A group of extraterrestrial botanists, who frequents the earth, are one night compelled to retreat hurriedly as humans trace their presence. Only on their retreat do they realize that one of them, called E.T, has been left behind. Back on Earth, E.T finds him alone, trying to comprehend the ways of this `oh-so-new` world. To his relief, he meets and is befriended by Elliot, a 10-year-old. Their relationship grows into a strong bond, rendering them inseparable. However, Elliot has to help E.T to trace a way to communicate with his kin. However, scientists plan on holding E.T back, making him a subject of experimentation. Will Elliot be able to protect his friend from their evil intentions, and help him go back home?