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Manthrikan depicts an unemployed man who`s trying to get rid of an evil spirit. This comic thriller stars Jayaram as the leading actor with actress Poonam Bajwa opposite him. The film`s supporting cast includes Riyaz Khan, Suraj Venjaramoodu, Sukanya, Natasha, Anil Murali, Priya, Mukta and Saddiq.
Anand Kumar has produced the film under the banner of Yes Cinema Company and SRT Films. The film`s screenplay has been written by Rajan Kiriyathu while S.Balakrishnan has composed its music score.