Minchu is the story of Ganesha, a sincere student studying medicine. At one instancem he is compelled used force and stop an unjust act from played on a friend. Madhevi, one of the spectators falls in love with his attitude and might, announcing her wish to marry him. Inspite of being told a several times by Ganesha that his focus is different, Madhevi keeps stressing on her romantic interest. In her pursuit, she loses her life, deeming Ganesha responsible. He is now on the radar of her brothers, against whom he must fight to prove his innocence and accomplish his dream of becoming a doctor.