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Poshter Boyz is a humorous take on a key social issue. The story is based on a real news piece, that the director Sameer Patil had read, about three men who find themselves on a poster advocating vasectomy and how their manliness comes under scrutiny. The film is humorous as well as deals with a serious issue in its own unique style. The film stars veteran actor Dilip Prabhavalkar, writer-actor Hrishikesh Joshi and Aniket Vishwasrao along with 48 actors in important character roles.