Rishi (Ritesh Deshmukh) and Anju (Genelia D`Souza) are best friends from childhood. They were born on the same day, in the same hospital. Their parents are also best friends and neighbours. Rishi and Anju are inseparable, so much so that they study in the same college and in the same class. This film marked the debut of Riteish Deshmukh and Genelia D`Souza and is a remake of a Malayalam blockbuster, Niram directed by Kamal.