Uday Shetty (Nana Patekar), Majnu (Anil Kapoor) and their boss, Sikander (Feroz Khan), three Hong Kong-based serio-comic Dons, are keen to get their sister Sanjana (Katrina Kaif) married into a respectable family.
Uday, upon a chance meeting with a handsome bachelor, Rajiv (Akshay Kumar), is convinced that the latter would be an appropriate match for Sanjana. The same series is followed by the rest of the brothers who like the same guy.
Meanwhile, Sanjana, unaware of her brothers` contrivances, meets Rajiv on a cruise and the two falls in love. She has the acceptance of Dr. Ghunghroo (Paresh Rawal) who is Rajiv`s uncle doesn`t realize that she is the sister of the Mafia.This fall-down funny comedy takes another turn when a stunning bomb (Mallika Sherawat) who claims to be Rajiv`s fiancee shows up on the scene and adds to the commotion and mayhem adding up to the laughing out your guts factor.