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A 29-year-old IT professional, Aakash, who leads a near perfect life, accidentally bumps into Ananya, an actress, who, unlike him, leads a rather messy, imperfect yet classy life. What follows their unexpected first meeting, is a friendship that soon blooms into a serious relationship through novel situations across Mumbai, Nashik, and Pune.
They both sail through different perspectives of families of both sides and get married in small but classy function. At the stroke of marriage, their careers take a drastic positive turn and they start enjoying their workspaces, which in turn affects their personal lives and relationship with each other. What's Up Lagna is about how the two, despite the twists and turns, manage to pull through the hard times in a realistic and relatable manner.