He is an accomplished concert pianist, music composer, and singer with a command of Indian and Western classical/semi-classical music, jazz, rock and pop music. Adnan Sami's most notable instrument is the piano. He has been credited as "the first musician to have played the santoor on the piano".
He is the fastest keyboard player in the world and called him the keyboard discovery of the nineties. Sami's songs and albums have always been admired and lionized by the people. Some of his bestselling albums are Kabhi to Nazar Milao and Sargam where he collaborated with renowned playback singer, Padmavibhushan Asha Bhosle.
The song "Tu Sirf Mera Mehboob" from the Hindi film Ajnabee, sung by Adnan, became popular and was declared a "superhit" by Screen Magazine, who called him the pop personality of the year in 2001.
Sami is the "most successful face in non-film music in India". Sami has won many national and international awards viz. the Bolan Academy Award, the Nigar Award, the Naushad Music Award" etc. In 2008 he also won "Best International Act" at the UK Asian Music Awards. Adnan Sami has performed for prestigious music festivals to sold-out stadiums of his solo concert tours all over the world in over forty countries. For his exceptional and commendable contribution in the music industry, the Indian media dubbed him the "Sultan of Music".