Atrangi Re is a story of a helpless mother who has 3 hopeless sons, each one having one bad habit. Her wish is to get them married and bring home a daughter in law. But as all of the three sons have bad habits of giving bad words, watching disgraceful videos and listening to loud music, no girl is ready to marry them. The drama unfolds the story of the life of the three sons and their unsuccessful comic struggle to fulfill the wish of their mother while meeting different girls. One girl who has run from the orphanage has an unpleasant story of her past meets them and their lives change forever.
The overall drama is full of entertainment and a roller coaster of comedy with elements of tragedy and revolution.