From an office boy to a National Award-winning director, Pandiraj is an acclaimed filmmaker of Tamil cinema. Pandiraj, who began working as an office boy for director K. Bhagyaraj, later assisted several directors such Cheran, Thangar Bachan, and Chimbu Devan. In 2009, he made his directorial and writing debut with the movie Pasanga, which featured several new child actors. The movie which was critically acclaimed won several awards including the National Film Award for Best Feature Film in Tamil and the Tamil Nadu State Film Award for Best Film. He has since then written and directed movies such as Vamsam (2010), Kedi Billa Killadi Ranga (2013), Pasanga 2 (2015), and Kathakali (2016).

In 2012, Pandiraj established his own production studio named Pasanga Productions: the first movie of the production house being Marina (2012) directed by Pandiraj himself. The production house has since produced movies such as Idhu Namma Aalu (2016) and Saraahsudu (2017). His 2019 releases include Sema, Kadaikutty Singam and Namma Veetu Pillai.