Known for her work in Malayalam film and TV industry, Amala Rose made her acting debut on the silver screen with the Malayalam neo-noir crime film Theevram (2012) where she played a supporting role. She subsequently appeared in Malayalam TV Series like Paadasaram (2013) and Sthreedhanam (2014). Her 2017 release include Oru Kanavu Pola, a Tamil action film directed by VC Vijay Shankar.