In a showbiz career spanning around two decades, Bill Gerber has been associated with the production of over 20 feature films and tv shows, including the Emmy-nominated biographical drama television film James Dean (2001).

Notable movie credits as a producer include the comedy The In-Laws (2003), the buddy comedy road film The Dukes of Hazzard (2005), the comedy Beerfest (2006) and the sports comedy Grudge Match (2013). In 2018, Gerber bankrolled the musical drama A Star is Born, which featured Bradley Cooper and Lady Gaga in central roles.