Model-turned-actress Chandrayee Ghosh made her feature film debut in 2004, with the Bengali movie Mahulbanir Sereng. Her work in Mahulbanir Sereng earned Chandrayee the Bengal Film Journalists` Association Award for Most Promising Debutante that year. Since then, the actress has established herself as a familiar face in Bengali cinema and television courtesy of her performances in movies like Dosar (2006) and Kaal (2007); and shows like Labonor Sansar and Behula.

Other significant acting credits include Necklace (2011), Tiyasha (2013) and the 2018 Bollywood romantic drama His 2019 release includes Bhobishyoter Bhoot, directed by Anik Dutta.