Following the footstep of his father, popular Malayalam film director Kamaluddin Mohammed Majeed, Jenuse Mohamed made his directorial debut with the 2015 Malayalam romantic comedy 100 Days of Love, which he also penned down. The film, starring Dulquer Salmaan and Nithya Menen, was a commercial and critical hit. His next project is the Malayalam sci-fi horror 9 (2019). The film has Prithviraj Sukumanran and Prakash Raj in the lead roles.