Making her foray into the film industry, Kheya Chattopadhyay was first seen in the 2015 Bengali drama Dwitiyo Ripu, co-starring Bitan Biswas, Biswajit Chakraborty, and Debashree Chakraborty. The same year, Kheya appeared in the thriller Bheetu: Coward, where she played the role of Priya. In 2017, she was cast alongside Aditya Sengupta and debutante Ishaa Saha in the romantic comedy Projapoti Biskut. Her 2020 release includes Abyakto.