Making his film debut in 2006 with the fantasy comedy-drama Lage Raho Munna Bhai, Rajesh Shantilal Khatri is an Indian actor who has worked mainly in the Hindi film industry. Since making his debut, Rajesh has acted in movies like Ghajini (2008), Delhi Belly (2011), Holiday (2014), Mastizaade (2016), Poster Boys (2017), and Blackmail (2018). He also worked in Gujarati films like Chal Man Jeetva Jaiye (2017), Dhaakad (2018), GujjuBhai: Most Wanted (2018), and Ani Maane (2018). Rajesh is married to Sangeeta Khatri.

In 2018 Rajesh acted alongside Zalakkumar Patel, Aishwarya Naik, Nihal Patel, Simran Arora, Henish Jariwala, and Toral Sharma in debutant filmmaker Chandradhar Rao Putta's Gujarati mystery-thriller, "Joothanu?". Rajesh plays the college principal in the movie.