Ram Pothineni, nephew of eminent film producer Sravanthi Ravi Kishore, has predominantly worked in the Telugu film industry. He made his acting debut in commercial hit film Devadasu (2006). He won Filmfare Award for Best Male Debut - South for the same. After such a smashing break, he became a household name. His credible performances including Ready (2008), Maska (2009), Kandireega (2011), Pendaga Chesko (2015) and Nenu Sailaja (2016), Vunnadhi Okate Zindagi (2017), Hello Guru Premakosame (2018) and iSmart Shankar (2019) and
Red (2021). His other notable works include The Warrior (2022).