Sachin Khedekar is an Indian actor and director. He made his debut in the Marathi film Jeeva Sakha (1990), but is best known for his roles in the films Astitva (2000) and Netaji Subhas Chandra Bose: The Forgotten Hero (2005). Some of his other significant works include Me Shivajiraje Bhosale Boltoy (2009), Singham (2011), Fakt Ladh Mhana (2011) and Aazaan (2011).

Khedekar started as a theatre artist who started acting in plays in 1985. His first play was Vidhilikhit. He then got into Hindi television through the show Imtihaan in 1995. He is also known for his role in the TV show Sailaab. He hosted the Marathi version of the TV show Kaun Banega Crorepati called Kon Hoeel Marathi Crorepati.

He was later seen in the films Krrish 3 (2013), Nagrik (2015), Shutter (2015), Rajwade and Sons (2015) and Laathi (2015). His 2016 ventures were Loveshhuda, Traffic and Rustom. His 2017 projects include Nenu Local, a Telugu movie, directed by Trinadharao Nakkina.He is associated with the upcoming 2017 movie FU: Friendship Unlimited. He has lent his voice in the 2018 Marathi animation Prabho Shivaji Raje directed by Nilesh Muley.

His other releases include Yatra (2019), the biographical drama NTR: Mahanayakudu (2019), Lucifer (2019), Pal Pal Dil Ke Paas (2019), Golkeri (2020), Radhe Shyam (2022), Dhamaka (2022), Shehzada (2023), Shaakuntalam (2023), Kushi (2023), Juna Furniture (2024), L2: Empuraan (2024) and Mumbaikar (2024).