Vandana Gupte is an Indian actress. She is most widely known for her performances as a Marathi stage artist, though she has appeared in films and television serials as well. She made her feature film debut with the Marathi movie Lapandav in 1993. Her other notable performances include Pachhadlela (2004), Meerabai Not Out (2008), Bandhan Saat Janamon Ka (2008/2009), Samaantar (2009) and Andhali Koshimbir (2014).

Vandana appeared in the Marathi comedy-drama Bucket List (2018) and 66 Sadashiv (2019).