In the course of a film career spanning over a decade, Bijukuttan has essayed a number of memorable comedic characters that have endeared him to the Malayalam cinema audience. He made his feature film debut in the 2006 comedy-drama Pothan Vava, and has since appeared in over fifty movies.

The action-comedy Chotta Mumbai (2007), Annan Thambi (2008), the comedies Aadu Oru Bheegara Jeeviyanu (2015) and Kunjiramayanam (2015) are among Bijukuttan`s notable acting credits. Significant film credits in recent times include the sports comedy Godha (2017), Aadu 2 (2017) and Suvarna Purushan (2018). His 2019 release includes Kantharam, directed by Shan Kechery.