Dancer-turned-actress Radhika Madan first rose to prominence with her award-winning performance in the soap opera Meri Aashiqui Tum Se Hi (2014-`16), which also marked her acting debut. The show, which was loosely based on Emily Bronte`s novel Wuthering Heights, had Radhika essaying the female lead; a performance that won her accolades at Zee Gold Awards and Indian Telly Awards in 2015.

In 2018, the actress made her feature film debut with Vishal Bharadwaj`s Pataakha. The comedy-drama, which followed the story of two sisters who shared a difficult relationship, had Radhika essaying the central role alongside Sanya Malhotra. Besides this, she has also appeared in the action comedy Mard Ko Dard Nahi Hota (2019), which was directed by Vasan Bala. Her 2020 release includes Angrezi Medium.