The son of filmmaker Chris Jupe and actress Katy Cavanagh, Noah Jupe began his career at the age of ten, with minor roles in acclaimed shows like Penny Dreadful (2015) and Downton Abbey (2015). This was followed by key roles in the mystery drama Houdini & Doyle and the crime-drama The Night Manager, which eventually led to his feature film debut in the biographical war drama The Man with the Iron Heart (2017).

Jupe has since made his mark in Hollywood courtesy of his performances in the black comedy Suburbicon (2017) and the drama film Wonder (2017), and he was nominated for a London Critics Circle Film Award for Young British Performer of the Year in 2018. In the same year, the young actor played a central role in the horror thriller A Quiet Place, which starred John Krasinski and Emily Blunt in the lead roles and opened to near-universal critical acclaim. He reprised the role in the film`s sequel A Quiet Place - Part 2, in 2021.